Lauren and Luis’s journey began in April 2017 when they agreed to stop using contraceptives and begin trying to start a family. However, nothing happened right away. Once Lauren reached cycle day 90, they decided to see a doctor to check what’s going on. After a blood draw, it was concluded that Lauren’s testosterone level was higher than it should be. She was not ovulating so she was subsequently diagnosed with Polycystic Ovarian Syndrome (PCOS).

Over the next year or so, Lauren and Luis endured seven medicated cycles with the drug Femara and never obtained a positive pregnancy test. Together they cried, prayed and felt absolutely broken. They wondered why getting pregnant was so easy for everyone else, but so hard for them.

Following the final failed Femara cycle, they decided to switch clinics on their quest for answers and a new plan. After a hysteroscopy, a semen analysis, more bloodwork and vaginal ultrasounds, the couple was diagnosed with unexplained infertility. They also learned that Lauren has a dual MTHFR gene mutation, which means her body cannot absorb folic acid and for that reason, is more prone to blood clots, reoccurring miscarriages and birth defects, if left untreated.

Lauren and Luis’s new treatment options were IUI or IVF. They decided not to do any IUI’s since their previous Femara results were less than ideal. They chose IVF.

Lauren and Luis went through the IVF ovarian stimulation process in November 2018 which included 24 abdominal injections, four blood draws and four ultrasounds in ten days. On December 4th they had their egg retrieval. From the 13 eggs collected, 9 fertilized and then after a few more days of growth, they ended up with three precious embryos.

Their first frozen embryo transfer date was set for January 9th, 2019, but in true infertility fashion, another roadblock came their way: there was fluid in Lauren’s endometrial lining so their transfer was cancelled just two days before the date it was supposed to take place. They were heartbroken, again, but they knew they were closer than they had ever been before.

Following the cancelled transfer, they knew they could not risk losing an embryo on poor lining or if Lauren’s implantation window was off, so they decided to be extra cautious and do an Endometrial Receptivity Analysis in March. The results of that test concluded than Lauren was pre-receptive, which meant she needed one extra day of progesterone for the embryo to implant. These results go against the normal progesterone protocol, which means any transfer they would have had prior to obtaining this knowledge would have failed.

The following month, Lauren and Luis had their first embryo transfer on April 17, 2019. They transferred one embryo and are currently in the two week wait, awaiting their HCG pregnancy blood draw on May 1st. They are happy, hopeful and praying they will have a baby in their arms in nine months.

Lauren M., Houston, TX

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